Find all press releases related to Cellecta here.
October 23, 2012 (PRWeb)
Cellecta received a Phase II SBIR contract from the National Cancer Institute to identify combinations of DNA damage and repair genes that are essential for cancer cells. There is great interest in these lethal gene combinations for drug development since therapies targeting multiple genes simultaneously can be much more effective at minimizing acquired resistance to a treatment over time. However, identification of these pairs is problematic using standard serial assays. Cellecta’s pooled RNAi screening solves this problem.
September 22, 2011 (PRWeb)
Cellecta receives a two-year $1.85M Phase II NIH/NCI SBIR grant to identify novel drug targets which interact with small molecules specifically lethal to hematopoietic cells. It is anticipated that this study will provide a basis to develop therapeutic treatments for blood cancers.
May 17, 2011 (PRLog)
In association with the DECIPHER Project, the non-profit plasmid repository Addgene is now distributing a set of short hairpin RNA (shRNA) pooled libraries to the academic community. Altogether, the libraries cover over 15,000 human genes and nearly 10,000 mouse genes (http://www.addgene.org/decipher)
February 24, 2011 (PRWEB)
Cellecta, Inc. released the 3rd Module of the DECIPHER Project Pooled shRNA Library which targets an additional 5,000 human genes. This new Human Library Module adds additional cell surface, extracellular, DNA binding targets, and other genes to the well-annotated signal transduction and disease-associated genes primarily targeted with the first two modules of the human shRNA library.
October 28, 2010 (PRWEB)
Cellecta announces the DECIPHER Project–an open source platform for genome-wide RNAi screening and analysis that provides free-of-charge access to shRNA libraries and software for genome-wide functional screening for researchers from academic and non-profit institutions.
September 30, 2010 (PRWeb)
Cellecta has received a $200K SBIR contract from the NCI to identify combinations of genes that, when silenced together, trigger death of cancer cells. These synthetic-lethal gene combinations can be difficult to identify with standard screening approaches, but Cellecta’s pooled lentiviral shRNA gene-suppressor library platform can be readily adapted for these types of anticancer drug target combinatorial screens.
September 16, 2010 (PRWeb)
Cellecta, in collaboration with The Scripps Research Institute, starts the next phase of its project to find new breast cancer drug targets by using its pooled lentiviral gene suppressor libraries to screen human isogenic mammary epithelial (HMEC) cells in genome-wide scale.
August 16, 2010 (GenomeWeb)
Ariadne, Cellecta, and the Roswell Park Cancer Institute today announced they will collaborate to develop a knowledgebase of prostate-specific pathway models. Under the agreement, Cellecta will use its DECIPHER™ functional genomics technology to screen for a panel of prostate cancer cell lines to identify genes that are essential for cancer cell viability. From that, Ariadne will use available ’omics data to identify the pathways involved and to “build mechanistic models in support of the genes identified from the siRNA targets in the screen,” the Rockville, Md., company said in a statement.
September 16, 2009 (PRWeb)
Cellecta issued a press release announcing that the company has been awarded a subcontract to assist the scientists at Roswell Park Cancer Institute and Health Research, Inc. in developing a new technology for the discovery of cancer-related genes using HT insertional mutagenesis.