DriverMap Immune Repertoire Profiling (iRP) Service

The DriverMap Immune Repertoire Profiling (iRP) Service from Cellecta provides you with a profile of all TCR and BCR CDR3 regions in blood, cell, or RNA sample.

With the DriverMap iRP service, you get

  • a larger complement of clonotypes than other similar assays
  • reproducible and comprehensive coverage from a range of sample inputs, including total RNA from whole blood
  • Rapid, 1-month turnaround

General information

Cellecta’s DriverMap™ iRP assay is designed to specifically amplify only functional CDR3 RNA molecules' TCR and BCR cells, avoiding non-functional pseudogenes with similar structures. The assay simultaneously amplifies, in a single multiplex RT-PCR reaction, all TCR and BCR CDR3 regions using a set of 300 experimentally validated PCR primers to yield Illumina-compatible next-generation sequencing (NGS) libraries.

Additionally, samples submitted for profiling using the DriverMap iRP service can be run, in parallel, through our standard DriverMap Gene Expression Profiling Service to generate gene expression profiles that provide phenotypic information for cell typing.

Do you have samples you would like to profile? Provide us with some information on your samples and your study goals, and we will get back to you about early access to our DriverMap Immune Repertoire Profiling program.

Download the product flyer for more info.

 

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