DriverMap™ Targeted Expression Profiling Panels For Single Cell Genomics
Expertly curated sets of genes to get the most insightful RNA expression profile
Providing a simple, sensitive snapshot of the up- and down-regulated genes in complex samples Go from total RNA to highly sensitive expression data in an Excel spreadsheet. Fast and Simple.
Try DriverMap Expression Profiling Panels to easily profile your samples, using expertly curated sets of genes whose expression levels provide insights on cancer and inflammatory diseases, cell signaling, cell lineages, processes of differentiation and immune activation.
- Expertly curated key genes provide insight on specific human diseases, cell phenotypes, cellular processes or disease progression.
- Ultra-sensitive quantitation of genes for single cells or precious samples with limited quantity of total RNA.
- Analyze the RNA expression in FACS-sorted cells directly in 96- or 384-well collection plate.
- Targeted gene sets require fewer NGS reads for gene targets, saving money.
- Targeted gene sets require fewer NGS reads for gene targets, saving money.
DriverMap Predesigned Panel Kits come with all the reagents you need to produce sequence-ready libraries for 96 samples on the Illumina NextSeq and other models.
Trying out DriverMap kit for the first time?
Learn how Harvard Professor Lester Kobzik is using DriverMap transcriptome profiling for cancer drug screening applications.
How the DriverMap™ Assay Works
How the DriverMap™ Assay Works
1. Human Cell Marker Panel
Cell Marker Panel analyzes 1,285 genes that are present in 64 different cell types spanning adaptive and innate immunity cells, hematopoietic progenitors, epithelial cells, and extracellular matrix cells.
2. Human Hallmark Signature Panel
Hallmark Signatures Panel profiles expression of 4,304 genes involved in well-defined molecular pathways, biological states, or disease processes.
3. Human LINCSx Panel
LINCSx Panel profiles expression of 1,573 landmark genes in LINCS database that catalog changes that occur when cells are exposed to drugs and other perturbing agents. Genes linked to targets for FDA approved drugs and related targets and markers.
4. Human Pan-Caner Pathway Panel
Pan-Cancer Pathway Panel analyzes 2,094 gene expression levels involved in pathways often dysregulated in cancer.
5. Human Transcription Factor Signatures Panel
Transcription Factor Panel provides data for 6,401 possible regulatory pathways by linking 343 distinct transcription factors to 2,649 target genes.
Analysis of a subset of cell-specific genes enabled clear differentiation of the cell types in each well. 10 ug of control RNA isolated for each cell type was included in the assay as a control.
How the DriverMap™ Assay Works
Check out DriverMap™ Mouse PanCancer / LINCSx / Hallmark Expression Profiling Panel