InDOXible™ Tet-Activated Lentiviral Expression System
InDOXible™ Tet-Activated cDNA Lentiviral Expression System
Convenient Doxycycline-inducible cDNA expression with no clonal selection required.
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All-in-one or two-vector system
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Optional fluorescent sensor for real-time monitoring of induction and repression
- Easy to use
How does it work?
Fusion of a bacterial tet-repressor protein with the VP16 activating domain creates a transactivator that binds--in a tetracycline-dependent manner--the tet-responsive element (TRE) derived from bacterial promoters.
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Cellecta-optimized transactivator ensures tightly regulated activation of the minimal CMV promoter driving expression of the cDNA, resulting in low background
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Two variations of the tetracycline activator--tTA or rtTA--enable activation with the addition or depletion of doxycycline
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Lentiviral backbone allows easy and effective introduction into mammalian cell lines
Available as an all-in-one or two-vector system with optional fluorescent sensor to enable real-time monitoring of induction and repression.
Simplify your inducible expression experiments today.
Single-vector Tet system >
Two-vector Tet system >
Product flyer: InDOXible Tet-Activated Lentiviral cDNA Expression system
Product details:
Single-vector Tet system >
Two-vector Tet system >
