2018 American Association for Cancer Research (AACR) Annual Meeting

April 14-18, 2018, McCormick Place Convention Center, Chicago, IL Come see us at Booth 2421. Technology Workshop: Monday, April 16, 2018, 10:00-11:00 am Genetic Profiling and Functional Screening for Drug Target and Biomarker Discovery Presenters: Sylvain Baron, PhD, Research Scientist and Paul Diehl, PhD, COO, Cellecta Lester Kobzik, MD, Professor of Pathology, Brigham and Women’s Hospital, Harvard Medical School Cellecta offers two technology platforms for rapid, precise, and convenient analysis of the genes responsible for driving various biological responses. The combination of multiplex RT-PCR with NGS provides the basis for our DriverMap™ Expression Profiling Assay, which measures expression levels of all human protein-coding genes in a simple-to-run, single-tube assay, enabling rapid association of gene expression changes in large numbers of cell, tissue, or blood samples. Complementary to this, genetic screens with pooled libraries of CRISPR sgRNA provide a more direct means to identify specific genes that functionally modulate observed phenotypic changes. Examples of how these approaches have been applied for target discovery, drug screening, and biomarker discovery will be discussed. Space is limited. Register for the Cellecta AACR Technology Workshop here> Poster: Targeted single-cell RNA expression profiling for cellular characterization of the tumor microenvironment

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