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- Tissue 2 Target Service
Catalog #: CRGC-PS
With Cellecta’s Single-Cell CRISPR Screening Service (aka Perturb-Seq, CRISP-Seq, CROP-Seq, etc.) you can study the effect of CRISPR-based perturbations on mRNA expression in many thousands of cells using single-cell RNA sequencing (scRNA-Seq) on the 10X Chromium system. This method can provide important insights into the transcriptional response resulting from genetic mutations and other perturbations that affect gene function.
Cellecta offers its Single-Cell CRISPR Screening Service on the 10X Chromium Controller Platform, which allows for screening of multiple genes in a single experiment and enables the identification of transcriptional profiles linked to specific gene perturbations.
We carry out all the services required to run most screens onsite, including construction and packaging of custom pooled sgRNA libraries, single-cell RNA-Seq on our in-house 10X Chromium and Illumina sequencing instruments, alignment of reads to identify hits, and post-screening analysis.
Single-Cell CRISPR Screening workflow