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Lentiviral constructs expressing sgRNA sequences can be transduced into cells with Cas9 variants and dCas9 variants to knock out, knockdown (CRISPRi), or activate (CRISPRa) gene expression in vivo or in vitro.
Cellecta offers a range ofconstitutive and induciblelentiviral vector backboneswith different selection and fluorescent markersfor cloning and expression of sgRNA.
If youcan’t find a suitable expression construct,Cellecta may be able to make it for as a custom constructs.
