March 29 – April 3, 2019, Georgia World Congress Center, Atlanta, GA
Come see us at Booth 4218.
I. Poster Abstract 3426: Tuesday, April 2, 2019 – 8:00 a.m. to 12:00 p.m.
Combining cell barcoding and CRISPR sgRNA libraries with targeted gene expression for single-cell genetic analysis of tumor metastasis
II. Educational Workshop: Spotlight Theatre C, Tuesday, April 2, 2019, 3:00-4:00 p.m.
Genetic Profiling and Functional Screening for Drug Target and Biomarker Discovery
Speaker 1: Paul Diehl, PhD, COO, Cellecta
Talk: Efficient tools to enable drug target and biomarker discovery: a brief introduction to Cellecta technologies
Speaker 2: Ian P. Winters, PhD, Director of Research, D2G Oncology
Talk: Quantitative and multiplexed in vivo functional cancer genomics using barcoded CRISPR libraries
Large-scale sequencing of human tumors has uncovered a vast array of genomic alterations. Genetically engineered mouse models recapitulate many features of human cancer and have been instrumental in assigning biological meaning to specific cancer-associated alterations. However, their time, cost- and labor-intensive nature limits their broad utility; thus, the functional importance of the majority of genomic aberrations in cancer remains unknown. Here, we combine genetically engineered mouse models of cancer with CRISPR-mediated genome editing, DNA barcoding, and next-generation sequencing to simultaneously investigate the function of many genomic alterations in vivo and uncover novel biological and clinically actionable insights into carcinogenesis.
Register here. Space is limited.View Event
April 24-29, 2020, San Diego Convention Center, San Diego, CA