CHI Discovery on Target

September 27-30, 2021, Sheraton Boston Hotel, 39 Dalton St., Boston, MA

Visit us at Booth # 204

Talk: Thursday, September 30, 2021, 1:10 pm to 1:40 pm – Track: Genomic Tools for Elucidating Novel Targets

Flexible and Scalable Genetic Screens for Novel Therapeutic Target Discovery

Measurements of changes in gene activation and expression provide a basis to understand genetic changes causing biological responses. Cell-to-cell gene disruption induced by CRISPR and other gene-perturbation technologies help tease out the drivers of these responses. Adaptations of these two screening approaches can be used to discover the genetic drivers responsible for phenotypic variabilities such as drug sensitivities and disease variation across tissue microenvironments, and between single cells.

Presenter: Paul Diehl, PhD, Chief Operating Officer, Cellecta

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