Date: Wednesday, October 28, 2020
Time: 8:00 am - 9:00 am USA Pacific Time (PDT); 10:00 am - 11:00 am USA Central Time (CDT); 4:00 pm - 5:00 pm Central European Time (CET)
Speakers: Johnathon Rose, MD Anderson Cancer Center; Sanjana Srinivasan, MD Anderson Cancer Center; Dr. Paul Diehl, COO, Cellecta
Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy, in part attributed to recurrence following standard-of-care treatment. In this webinar, the speakers will discuss the development of an integrated platform to inform on intra-tumoral vulnerability context from gene-cluster trends.
Leveraging a representative patient-derived xenograft cohort, the platform was used to integrate a PDAC co-expression network (PCEN) with customized in vivofunctional genomics to define cluster-anchored vulnerabilities. This enabled characterization of PCEN representation intra-tumorally, and feature-barcoded, single-cell analysis was then used to validate subcellular targeting following PCEN-informed CRISPR perturbation.
In this webinar, you will learn:
A brief overview of Cellecta technologies and live Q&A session will follow the presentation.