DriverMap™ AIR TCR-BCR Profiling Kit (Mouse RNA)

Easy-to-run, single-day assay that uses multiplex qRT-PCR and NGS to profile expressed T-cell receptor (TCR) and/or B-cell receptor (BCR) repertoire of CDR3 region from mouse RNA samples. The DriverMap AIR RNA-based assay allows sensitive detection of the immune receptor repertoire, which is especially important in identifying rare TCR and BCR clonotypes. The DriverMap AIR TCR/BCR Profiling Kit for Mouse offers:

• The most comprehensive profile of the CDR3 regions of all  hyper-variable TCR chains (TRA, TRB, TRG, and TRD) and BCR chains (IGH, IGK, and IGL) in a single reaction from a single sample (Fig 1).
• Sensitive and reproducible profiling of samples across multiple sample types such as PBMC, whole blood, tissue, or FFPE samples.
• All-inclusive kit contains all the enzymes, reagents, and primers to prepare NGS-ready libraries from 24- or 96- samples of total RNA.
• Analysis pipeline on MiXCR software (MiLaboratories, Inc.) for adaptive immune profiling

Manual and Product Resources

• Manual: DriverMap AIR RNA Profiling Kit Manual - for the AIR RNA kits profiling the CDR3 regions.
• Technology Guide: DriverMap AIR Technology Guide for an introduction to AIR technology and for recommendations on designing an AIR profiling experiment
• Product Flyers and Other Resources:
• Flyer: Comprehensive Adaptive Immune Receptor Profiling for All Immune Sample Types
• Brochure: DriverMap Technology Solution
• Video: Improved Adaptive Immune Receptor Repertoire Profiling for Biomarker Discovery (23:08)