Catalog #: DMAIR-HTD-24

DriverMap™ AIR TCR-BCR Profiling Kit (Human DNA)

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Easy-to-run, single-day assay that uses multiplex PCR-NGS technology to profile T-cell receptor (TCR) or B-cell receptor (BCR) repertoire present in human DNA. The DriverMap AIR DNA assay measures the frequency of CDR3 clonotypes to quantify the clonal frequency of T and B cells.

  • Assay primers contain unique molecular identifiers (UMIs) to enable accurate quantitation of each clonotype.
  • Sensitive profiling of samples with low lymphocyte content (e.g. FFPE, tumor biopsy, achieved specimens) where DNA is more stable than RNA. 
  • Complete kit includes all the enzymes, reagents, and primers to prepare 24- or 96- samples ready for multiplex Illumina NGS runs from DNA starting material. No additional specialized equipment required.  
  • Parallel runs of DriverMap AIR DNA Assay with DriverMap AIR RNA Assay reveal potential disease-associated, activated CDR3 clonotypes
DriverMap™ AIR TCR samples (Human DNA samples) - Kits


Fig 1: Mean clonotype counts for four TCR chains from different DNA sample inputs.

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