April 17 - 22, 2026, at the San Diego Convention Center in San Diego, California
Stop by the Cellecta Booth #1928 (Exhibit Hall C entrance) and say hello!
Exhibit Hall Schedule
Sunday, April 19: 12:00 - 5:00 pm
Monday, April 20: 9:00 am - 5:00 pm
Tuesday, April 21: 9:00 am - 5:00 pm
Wednesday, April 22: 9:00 am - 12:00 pm
Schedule some time to meet with us at our booth! Or Join us at our presentations.
I. Exhibitor Spotlight Theater
Tuesday, April 21, from 10:00 - 11:00 am in Spotlight Theater E
Applications for TCR Repertoire Profiling: Bridging the Gap between Repertoire Frequency and Functional Specificity
This session explores end-to-end workflows for identifying tumor-reactive T cells.
- After a brief introduction to Cellecta's technologies presented by Paul Diehl, Cellecta chief operating officer, Alex Chenchik, Cellecta president and chief scientific officer, will discuss how to leverage Cellecta’s DriverMap AIR TCR profiling assays to detect antigen-expanded TCRs using bulk and single-cell sequencing to obtain chain-pairing information.
- Next, our invited speaker, Katharina Lindner, from the German Cancer Research Center (DFKZ), will introduce ESPEC-SUIT, a platform developed to bridge the gap between repertoire frequency and functional specificity. She will demonstrate the workflow by longitudinally tracking antigen-specific clonotypes across blood and tumor compartments in neoepitope-vaccinated glioma patients.
- By combining sensitive TCRβ sequencing with functional validation, our speakers show how characterizing TCR dynamics uncovers mechanisms of tumor rejection and resistance, accelerating the discovery of potent, tumor-reactive TCRs for immuno-oncology.
Introductory Remarks: An overview of Cellecta technologies
Paul Diehl, PhD, COO, Cellecta
Speaker 1: Alex Chenchik, Ph.D., Cellecta President & Chief Scientific Officer
From Repertoire to Response: A Workflow for Mapping Antigen-Driven T and B Cell Clonotypes
We will present an integrated immune profiling workflow that links repertoire sequencing with functional validation to rapidly identify antigen-specific T and B cell clonotypes. By combining bulk and single-cell AIR profiling with multiplexed receptor pairing and reporter-based screening, it enables high-confidence epitope discovery for immuno-oncology applications, biomarker development, and targeted immunotherapy design.
Speaker 2: Dr. Katharina Lindner, Postdoctoral Researcher, Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology at the German Cancer Research Center
Identification and Tracking of Antigen-Specific T Cell Receptors in Cancer Patients by High-Throughput TCR Sequencing
Granular profiling of antigen-specific T cell receptor (TCR) repertoires remains a challenge in cancer immunology. We describeESPEC-SUIT, a sequencing-based platform integrating peptide-drivenin vitro expansion of antigen-specific CD4⁺ and CD8⁺ T cells with TCR repertoire analysis. Antigen-stimulated cultures undergo bulk TCRβ sequencing to define expanded clonotypes, enabling downstream tracking, cloning and functional validation of TCRs. Applied longitudinally, ESPEC-SUIT captures dynamic changes in antigen-specific TCR repertoires and supports tracking of clonotypes across blood and tumor samples, which we demonstrate in a cohort of neoepitope-vaccinated glioma patients. ESPEC-SUIT enables scalable, comprehensive, and sensitive interrogation of tumor-reactive TCR landscapes for immuno-oncology research.
Register to attend in person >
Refreshments will be provided; space is limited
I'm unable to attend in person, please send me the recording of the talks >
Not affiliated with or endorsed by AACR. The Exhibitor Spotlight Theater is a promotional activity and is not approved for continuing education credit. The content of this Exhibitor Spotlight Theater and opinions expressed by presenters are those of the sponsor or presenter and are not of the American Association for Cancer Research (AACR).
II. Posters
Sunday, April 19, from 2:00 - 5:00 pm
POSTER NUMBER 0476: A practical workflow for adaptive immune receptor profiling and screening of antigen-specific clonotypes with applications in cancer
Presented by: Paul Diehl, Ph.D., Cellecta Chief Operating Officer
Poster Section 19, Poster Board 19
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Tuesday, April 21, from 9:00 am - 12:00 pm
POSTER NUMBER 4249: High-throughput discovery of MART1-specific TCR-peptide interactions using a Jurkat NFAT Reporter-K562 antigen-presenting cell system and single-cell adaptive immune receptor profiling
Presented by: Alex Chenchik, Ph.D., Cellecta President & Chief Science Officer
Poster Section 6, Poster Board Number 17
Abstract Number: 6807
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Tuesday, April 21, from 2:00 - 5:00 pm
POSTER NUMBER 6515: High-throughput, 96-well plate-based single-cell TCR sequencing for scalable chain-pairing and immunophenotyping of cancer-associated T-cells
Presented by: Alex Chenchik, Ph.D., Cellecta President & Chief Science Officer
Poster Section 43, Poster Board Number 4
Abstract Number: 5552
We look forward to seeing you at Booth 1928 in San Diego!
