CHI’s Discovery on Target

September 16-20, 2019, Westin Copley Place, Boston, MA

Stop by and see us at Booth 401.

Talk: Tuesday, September 17, 2019, 11:55 am to 12:25 pm – Track: Target Identification & Phenotypic Screening

Transcriptome Profiling and Functional Screening to Identify Genes Driving Biological Responses and Disease Progression

Pooled libraries of heterogenous lentiviral constructs have proven to be an effective approach to individually label cells in a target population with cell-specific barcodes and/or other genetic effectors. NGS analysis of targeted multiplex RT-PCR from cell samples enables parallel analysis of differences in gene activation as a result of perturbation. These approaches can be used to gain a more comprehensive understanding of genetic pathways in disease.

Presenter: Paul Diehl, PhD, COO, Cellecta