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disease

German Researchers Find Sensitizer for Gemcitabine Using DECIPHER RNAi Libraries

June 10, 2013

Researchers at the German Cancer Research Center (DKFZ) used Cellecta's shRNA DECIPHER libraries to identify genes that sensitize pancreatic cells to gemcitabine.Pancreatic cancer has only a 6% 5-year survival rate. Gemcitabine is the standard treatment in conjunction with surgery to remove cancerous...

Tissue Targeting May Offer an Alternative Therapeutic Approach for Difficult-to-Treat Diseases

October 14, 2011

Cancer disease drug targets lethal leukemia lymphoma NIH Pooled shRNA Library RNAi Screen RNAi Screening shRNA Library stem cell transplantation Synergistic Lethality synthetic lethality Synthetic Lethalitycancer

We recently received a phase II of our SBIR grant Exploiting Synthetic Lethality of Hematopoietic Lineage Cells to Develop Novel Targets from the NIH. Rather than trying to identify potential drug targets in oncogenic hematopoietic cells, much of the effort for this project focuses on trying to develop a...

Cellecta's DECIPHER Project RNAi Screening Tools at Roswell Park Cancer Institute

February 15, 2011

Cancer DECIPHER disease Pooled shRNA Library RNAi Screen RNAi Screening Roswell Park Cancer Institute RPCI shRNA Library signaling pathways TAM TAM Programcancer

Cellecta's recent agreement with the Roswell Park Cancer Institute (RPCI) provides support to laboratories in their institution doing genome-wide RNAi...