Cellecta Blog & News

We have started the Cellecta blog as a simple, unobtrusive conduit that enables us to talk directly to our customers, collaborators, and other interested researchers about new and interesting developments related to Cellecta’s technology and business. Check back here often for the latest news and events.

About Cellecta

Cellecta Inc., a custom and contract functional genomics solutions provider, focuses primarily on developing and implementing flexible and scalable broad-based screening and analysis approaches for drug target and biomarker discovery. Our high throughput functional genetic screening portfolio includes shRNA and CRISPR screening services, custom and off-the-shelf pooled libraries, and knockout/knockdown cell lines that facilitate genome-wide functional screening and the identification and validation of genes involved in critical biological and pathological responses.

With our new DriverMap™ Gene Expression and Molecular Profiling Service, Cellecta now offers a quantitative, multiplexed approach that allows simultaneous profiling of thousands of genes in one reaction, thereby providing the transcriptome profile of the tumor microenvironment.

RNAi Screening with An Inducible Promoter: Is There an Advantage?

May 13, 2011

Inducible expression is often desirable for functional genetic testing to establish clear cause and effect for a specific phenotype. A particular phenotype can be demonstrably linked to expression of a specific cDNA by showing it disappears when transcription is suppressed. Although less direct, similar logic...
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Ensuring Comprehensive Screening with Pooled shRNA Expression Libraries

April 03, 2011

Researchers are often interested in using a pooled shRNA library for genome-wide RNAi screening to cast a very “wide and unbiased net to identify any and all genes functionally involved in some pathway”. Although it is not difficult to make an shRNA library targeting all human or mouse genes, it is practically very...
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SBS 2011 Schedule, March 30th

March 30, 2011

Take the opportunity at SBS 2011 to learn about Cellecta's cancer drug target discovery services. Come visit us at booth #522, and be sure not to miss our oral presentation and tutorial on Wednesday, March 30:HT RNAi Screening of Anti-Cancer Targets With Pooled shRNA LibrariesSpeaker: Alex Chenchik, Ph.D.Alex...
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AACR-NCI Systems Biology Conference

March 12, 2011

Cellecta attended the AACR-NCI Systems Biology : Confronting the Complexity of Cancer Conference in San Diego last week and presented two posters:...
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The DECIPHER Project’s New Human Module Targets 5,000 More Genes

February 25, 2011

The addition of the 3rd DECIPHER Human shRNA Expression Library Module to the DECIPHER pooled shRNA library collection adds approximately 5,000 new cell surface, extracellular, and DNA binding target genes...
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U6 or H1 - Which promoter is better?

February 18, 2011

Since we provide both constitutive and tetracycline-inducible versions of both U6 and H1 shRNA promoters,...
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Cellecta's DECIPHER Project RNAi Screening Tools at Roswell Park Cancer Institute

February 15, 2011

Cellecta's recent agreement with the Roswell Park Cancer Institute (RPCI) provides support to laboratories in their institution doing genome-wide RNAi...
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